A Vicksburg woman was killed Wednesday in a wreck on Interstate 20 near Clinton.

Hinds County Coroner Jeremiah Howard told media outlets that 53-year-old Tatyana Zavyalova, of Vicksburg, died at the scene when her car collided with an 18-wheeler around 2:30 a.m. Wednesday.

Howard said Zavyalova was returning from a trip to Florida when the crash occurred on I-20 West near the Springridge Road exit. The accident led police to close a four-mile stretch of interstate between Jackson and Clinton for several hours.

Howard said fatigue might have been a factor. A toxicology report has been ordered. The Mississippi Highway Patrol has not released any other details about the crash.